Senolytics
Insilico Wants to Build a “Longevity Vaccine.” Here’s What Actually Exists So Far
Insilico’s “Longevity Vaccines” initiative proposes programming immune cells inside the body. Related mouse studies are encouraging, but the announcement offers no programme-specific…
Natural Compounds Cleared Senescent Cells and Extended Lifespan in Old Mice
Salvianolic acids A, B and E selectively killed senescent cells and improved function and survival in aged mice, but there is no…
Senolytics Have a Measurement Problem. A New Roadmap Aims to Fix It
A new consensus roadmap calls for better biomarkers and precision senescence medicine. It is a research agenda, not proof that senolytics extend…
Whatever Happened to Senolytics?
Senolytics were once expected to clear the “zombie cells” of aging. A decade of human trials has produced intriguing biological signals, major…
Senescent Cells May Survive by Shedding Their Damaged Parts
Senescent cells may stay alive by shedding fragments that contain damaged mitochondria. The finding reveals a new survival mechanism, but no therapy…
The Immune System Already Hunts Senescent Cells. Can Scientists Make It Work Better?
Researchers are learning how senescent cells evade immune clearance—and how engineered immune responses might remove them. The strategy is compelling, but it…
Machine Learning Finds New Ways to Target Senescent Cells
Models narrowed hundreds of thousands of molecules to laboratory-tested candidates. That is an efficiency gain, not yet a medicine.