Medicine

AgelessRx Says a 90-Day Longevity Trial Improved Healthspan. What Did It Actually Show?
AgelessRx reported favorable changes from an 18-person final analysis. The randomized pilot generated signals, but it did not prove slower aging or…

Can Stem Cells Treat Frailty? A New Human Trial Tests the Idea
A randomized Phase 2b trial found that one laromestrocel infusion improved walking distance at nine months. It is promising human evidence, not…

Semaglutide Extended Lifespan in Old Mice. Does That Make It a Longevity Drug?
Semaglutide extended median lifespan by about 12% in older female mice. The result is compelling animal evidence, not proof of a human…

Scientists Find a Tiny Protein That May Help Protect the Aging Heart
A 47-amino-acid mitochondrial protein helped preserve heart structure and function in experimental models, but it is not an anti-aging treatment for people.

The Ovary May Be Keeping Track of How Many Eggs Remain
A 3D map of more than 85,000 mouse oocytes found that roughly 14% of the remaining reserve stayed in a transitional state…

Whatever Happened to Senolytics?
Senolytics were once expected to clear the “zombie cells” of aging. A decade of human trials has produced intriguing biological signals, major…

A Startup Says It Can Make Your Blood Younger. Where’s the Evidence?
Generation Lab says an undisclosed two-drug injection can make the body’s systemic environment younger. The scientific premise is plausible, but controlled human…

Sam Altman-Backed Retro Biosciences Moves Deeper Into Human Testing
Sam Altman-backed Retro Biosciences is advancing RTR242 through a Phase 1 trial in healthy volunteers. Here is what the trial can show,…

Your Eyes May Reveal How Fast You’re Aging: AI Finds a Retinal Signal in 71,000 People
AI estimated age from retinal photographs in 71,343 people. An older retinal signal tracked several health risks, but it is not a…

Brain Aging May Not Be Just About Neurons. Myelin-Making Cells Could Be Part of the Problem
Human brain tissue and mouse experiments point to oligodendrocytes, myelin and NRF2 as possible contributors to cognitive decline. No human treatment has…