Biological Age
Scientists Want a Speedometer for Aging. These 12 Signals Could Be the Start
Researchers propose 12 biological signals that might reveal whether aging is currently moving faster or slower. The candidates come mostly from mouse…
She Lived to 117. Her Biology Shows That Aging and Disease Are Not Quite the Same Thing
Maria Branyas carried clear molecular signs of extreme age alongside low inflammatory markers and other features associated with good health. Her detailed…
Higher Folate Tracked With Slower Biological Aging. That Does Not Mean Supplements Slow Aging.
In older adults from India, higher folate tracked with slower biological aging while higher homocysteine tracked with faster aging. The longitudinal study…
Your Gut Microbiome May Track Inflammaging Better Than Your Age
In 1,199 adults, gut microbiome composition tracked inflammatory and physiological differences more strongly than chronological age. The study is observational and does…
SIRT6 Gene Therapy Lowered Biological Age in Old Dogs, Genflow Says. Where Is the Data?
Genflow says its randomized, blinded trial lowered a DNA methylation age score in older beagles. The result is intriguing, but detailed numerical…
Six Biological Age Clocks Moved Younger After an AI-Designed Drug. Did Aging Actually Slow?
Rentosertib lowered predicted biological age across six protein-based clocks in a small pulmonary fibrosis trial. The result is intriguing, but it does…
People Age Along Different Biological Paths, an Eight-Year Study Finds
Repeated measurements in 335 women show that molecular aging can follow very different paths. The findings challenge simple averages, not establish a…
Your Organs Don’t Age at the Same Rate. Scientists Just Mapped 40 of Them
An AI analysis of more than 25,000 human tissue samples found that organs follow distinct structural aging trajectories, challenging the idea of…
A New Aging Clock Measures the Colon. Disease Seems to Speed It Up.
A tissue-specific DNA methylation clock estimated colon age with a 3.9-year mean error. Disease groups looked older, but the clock is not…
Longevity Medicine Is Arriving Before Primary Care Is Ready
Patients are asking doctors about aging clocks, rapamycin and senolytics before medicine has settled what to test, prescribe or monitor. Primary care…