Research
Evidence-first reporting on aging biology, longevity studies and the path from laboratory findings to useful human evidence.
Singapore Is Building a National Test Bed for Healthy Longevity
A S$350 million Grand Challenge connects aging research with real healthcare settings. Population studies and biomarker validation could help guide future care,…
Blocking Growth Hormone Signaling in Middle Age Extended Lifespan in Mice
Genetic disruption of growth hormone receptors at 12 months improved survival in male and female mice. The experiment does not establish a…
Aging Makes Retinal Regeneration Harder, Even When Cells Are Reprogrammed
Older mouse retinas produced fewer neurons after glial-cell reprogramming. Anti-inflammatory treatment helped partly, highlighting a barrier for regenerative medicine.
Frailty May Leave a Distinctive Signature in Blood DNA
Researchers found differences in cellular damage and circulating DNA in frail adults. A methylation analysis of only five selected people per group…
People Age Along Different Biological Paths, an Eight-Year Study Finds
Repeated measurements in 335 women show that molecular aging can follow very different paths. The findings challenge simple averages, not establish a…
Senolytics Have a Measurement Problem. A New Roadmap Aims to Fix It
A new consensus roadmap calls for better biomarkers and precision senescence medicine. It is a research agenda, not proof that senolytics extend…
Can Stem Cells Treat Frailty? A New Human Trial Tests the Idea
A randomized Phase 2b trial found that one laromestrocel infusion improved walking distance at nine months. It is promising human evidence, not…
Brown Launches $37 Million Healthspan Alliance to Push Aging Research Toward Patients
A five-year alliance will connect Brown’s aging laboratories with its health system’s clinical-trial network. The investment builds infrastructure, not proof of a…
Semaglutide Extended Lifespan in Old Mice. Does That Make It a Longevity Drug?
Semaglutide extended median lifespan by about 12% in older female mice. The result is compelling animal evidence, not proof of a human…
Scientists Find a Tiny Protein That May Help Protect the Aging Heart
A 47-amino-acid mitochondrial protein helped preserve heart structure and function in experimental models, but it is not an anti-aging treatment for people.