Aging Biology
Why Brown Fat Makes Less Heat in Aging Mice
An inflammatory signal held brown fat in a low-heat state in older mice. Blocking a hormone receptor partially restored their response to…
Why Do We Age If Our Cells Keep Replacing Themselves?
Cell replacement varies across the body. Long-lived cells, inherited DNA changes and aging tissue help explain why ongoing renewal does not prevent…
Kidney Disease Pushed Certain Cells Toward an Aging-Like Epigenetic State
A single-cell kidney atlas found aging-like epigenetic changes concentrated in tubular epithelial cells, especially in areas of unresolved repair.
Small AI Models Led an Aging-Biology Benchmark. What Does That Actually Mean?
A compact model led LongevityBench, a new test of AI on aging data. The gains are real, but benchmark rankings and proposed…
Natural Compounds Cleared Senescent Cells and Extended Lifespan in Old Mice
Salvianolic acids A, B and E selectively killed senescent cells and improved function and survival in aged mice, but there is no…
Senescent Cells May Survive by Shedding Their Damaged Parts
Senescent cells may stay alive by shedding fragments that contain damaged mitochondria. The finding reveals a new survival mechanism, but no therapy…