Inflammaging
Scientists Found One of the Body’s Natural Brakes on Inflammation
A small human study traced a fat-derived signaling pathway that limited inflammatory immune cells and hastened pain resolution. It did not test…
Your Gut Microbiome May Track Inflammaging Better Than Your Age
In 1,199 adults, gut microbiome composition tracked inflammatory and physiological differences more strongly than chronological age. The study is observational and does…
Senescent Cells May Survive by Shedding Their Damaged Parts
Senescent cells may stay alive by shedding fragments that contain damaged mitochondria. The finding reveals a new survival mechanism, but no therapy…
IL-38 Reduced Inflammatory Stress in Aged Mouse Immune Cells
IL-38 dampened inflammatory, oxidative and cell-cycle changes in macrophages grown from aged mice. The work was done in cultured cells and does…
A Probiotic Improved Healthspan in Old Mice. That Doesn’t Mean You Should Buy It Yet.
A bacterium depleted with age improved several health measures in old mice. Human intervention trials have not shown that it extends healthspan.
Scientists Tried Removing an Inflammaging Trigger. The Mice Aged Faster.
Deleting cGAS did not simply quiet age-related inflammation. In mice, it disrupted chromatin control, activated LINE1 elements and shortened median lifespan.