Mouse Studies
AI Points to PBX1 as a Clue to Why Blood Stem Cells Age
A mouse study used Geneformer and laboratory validation to identify PBX1 as one regulator of age-related changes in blood stem-cell output.
Scientists Tried Removing an Inflammaging Trigger. The Mice Aged Faster.
Deleting cGAS did not simply quiet age-related inflammation. In mice, it disrupted chromatin control, activated LINE1 elements and shortened median lifespan.