Geroscience
Scientists Want a Speedometer for Aging. These 12 Signals Could Be the Start
Researchers propose 12 biological signals that might reveal whether aging is currently moving faster or slower. The candidates come mostly from mouse…
Six Biological Age Clocks Moved Younger After an AI-Designed Drug. Did Aging Actually Slow?
Rentosertib lowered predicted biological age across six protein-based clocks in a small pulmonary fibrosis trial. The result is intriguing, but it does…
Singapore Is Building a National Test Bed for Healthy Longevity
A S$350 million Grand Challenge connects aging research with real healthcare settings. Population studies and biomarker validation could help guide future care,…
Blocking Growth Hormone Signaling in Middle Age Extended Lifespan in Mice
Genetic disruption of growth hormone receptors at 12 months improved survival in male and female mice. The experiment does not establish a…
The Ovary May Be Keeping Track of How Many Eggs Remain
A 3D map of more than 85,000 mouse oocytes found that roughly 14% of the remaining reserve stayed in a transitional state…
Whatever Happened to Senolytics?
Senolytics were once expected to clear the “zombie cells” of aging. A decade of human trials has produced intriguing biological signals, major…
Your Organs Don’t Age at the Same Rate. Scientists Just Mapped 40 of Them
An AI analysis of more than 25,000 human tissue samples found that organs follow distinct structural aging trajectories, challenging the idea of…
FGF21 Gene Therapy Extended Lifespan and Healthspan in Aged Mice
A one-time FGF21 gene therapy increased median lifespan by 20.54% in aged male mice and improved several measures of metabolic, organ and…
Longevity Medicine Is Arriving Before Primary Care Is Ready
Patients are asking doctors about aging clocks, rapamycin and senolytics before medicine has settled what to test, prescribe or monitor. Primary care…
The Hallmarks of Aging, Explained Without the Hype
The framework has become longevity science’s shared vocabulary. It is a map of interacting processes, not a checklist of proven human drug…